脑血管受损人群中医体质分布规律及血流动力学相关研究

Study on the Distribution Law of Chinese Medicine Constitution and its Correlation with Hemodynamics in Patients with Cerebrovascular Trauma

目的:观察脑血管受损人群中医体质分布规律及不同体质脑血管受损人群血流动力学指标之间的关系。方法:选取300例脑血管受损患者为研究对象,参考王琦教授9种基本中医体质类型标准进行分类,分别统计不同性别、年龄段人群的中医体质,比较常见中医体质类型患者左侧与右侧血流动力学指标[(平均血流量(Qmean)、平均血流速度(Vmean)、特性阻抗(Zcv)、外周阻力(RV)、动态阻力(DR)]。结果:脑血管功能受损人群中医体质类型所占比例排序:痰湿质>瘀血质>气虚质>气郁质>阳虚质>湿热质>阴虚质>特禀质>平和质。男性痰湿质患者所占比例高于女性,差异有统计学意义(P<0.05)。各年龄段脑血管受损患者中医体质类型所占比例最高的均为痰湿质,瘀血质次之。痰湿质患者左侧Q^(mean)、V^(mean)、Zcv、RV、DR优于右侧(P<0.05),湿热质、瘀血质、气郁质、气虚质患者左侧Qmean、Zc v、RV、DR优于右侧(P<0.05),阳虚质患者左侧Qmean、RV、DR优于右侧(P<0.05)。结论:脑血管功能受损人群以偏颇质为主,痰湿、瘀血是易感因素,男性患者痰湿质较女性更为多见,易感体质患者右侧脑血管弹性较差、血液黏稠度较大、血流速度较低。

Objective：To observe the distribution law of Chinese medicine constitution in patients with cerebrovascular trauma,and the relationship between patients with cerebrovascular trauma of different Chinese medicine constitutions and the hemodynamic indexes.Methods：Selected 300 cases of patients with cerebrovascular trauma as study subjects,and classified them according to the standard of nine basic types of Chinese medicine constitutions proposed by Professor WANG Qi.Respectively counted the Chinese medicine constitutions of different genders and age groups,and compared the hemodynamic indexes of both the left and right side in patients of common Chinese medicine constitutions,including mean blood flow,mean velocity,characteristic impedance（Zcv）,peripheral resistance（RV）and dynamic resistance（DR）.Results：The proportion of different Chinese medicine constitutions in patients with cerebrovascular trauma was ranked：phlegm-dampness constitutionblood-stasis constitutionqi-deficiency constitutionqi-stagnation constitutionyang-deficiency constitutiondampness-heat constitutionyin-deficiency constitutionspecial intrinsic constitutionbalanced constitution.The proportion of phlegm-dampness constitution in male patients was higher than that in female patients,the difference being significant（P〈0.05）.The highest proportion of Chinese medicine constitution in patients with cerebrovascular trauma in all age groups was phlegm-dampness constitution,followed by blood-stasis constitution.Levels ofand DR of the left side were better than those of the right side in patients of phlegm-dampness constitution（P〈0.05）.Levels ofand DR of the left side were better than those of the right side in patients of dampness-heat constitution,blood-stasis constitution,qi-stagnation constitution or qi-deficiency constitution（P〈0.05）.Levels ofand DR of the left side were better than those of the right side in patients of yang-deficiency constitution（P〈0.05）.Conclusion：Patients with cerebrovascular trauma are mainly of biased constitutions,and the phlegm-dampness and blood-stasis are susceptible factors.It＇s more common to see male patients of phlegm-dampness constitution than female patients.On the right side of the patients of susceptible constitutions have poor cerebrovascular elasticity,large blood viscosity and low blood flow velocity.