升白汤联合深部热疗防治化疗后骨髓抑制临床观察

Clinical Observation of Shengbai Tang Combined with Deep Thermotherapy Preventing Myelosuppression after Chemotherapy

目的:探讨自拟升白汤联合深部热疗防治化疗后骨髓抑制的临床疗效。方法:将73例恶性肿瘤患者随机分为治疗组37例和对照组36例。治疗组采用升白汤内服联合深部热疗治疗,对照组采用利可君片口服治疗。连续治疗3周后,检测2组治疗前和治疗后1周、2周、3周白细胞总数(WBC)、血红蛋白(Hb)、血小板(BPC)水平变化;比较2组临床疗效和生存质量改善率。结果:治疗后1周、2周、3周,2组WBC与治疗前比较,差异均有统计学意义(P<0.05);治疗后1周、2周,治疗组WBC与对照组比较均无差异(P>0.05);治疗后3周,治疗组WBC高于对照组(P<0.05)。治疗后3周,对照组Hb、BPC水平与治疗前比较无差异(P>0.05);治疗组Hb、BPC水平均较治疗前升高(P<0.05),与对照组比较亦升高(P<0.05)。治疗后,总有效率治疗组为91.9%,对照组为69.4%,2组比较,差异有统计学意义(P<0.05);生存质量改善率治疗组为9 4.6%,对照组为63.9%,2组比较,差异有统计学意义(P<0.05)。结论:升白汤联合深部热疗对化疗后骨髓抑制有改善作用,能明显提高患者的WBC、Hb和BPC水平,提高临床疗效,改善生存质量。

Objective：To discuss the clinical effect of self-made Shengbai tang combined with deep thermotherapy in preventing myelosuppression after chemotherapy.Methods：Divided 73 cases of patients with malignant tumor into the treatment group being 37 cases and the control group being 36 cases randomly.The treatment group was given oral Shengbai tang combined with deep thermotherapy for treatment,while the control group was given leucogen tablets orally.After continuously treating for three weeks,detected the levels of total number of white blood cells（WBC）,hemoglobin（Hb）and changes of blood platelet count（BPC）before treatment and at the 1st,2nd and 3rd week of treatment.Compared the clinical effect in two groups,and the improvement rate of quality of life in the two groups.Results：After one,two and three weeks of treatment,compared WBC in the two groups with those before treatment,differences being significant（P〈0.05）.After one and two weeks of treatment,there were no significant differences being found in WBC between the treatment group and the control group（P〈0.05）.After three weeks of treatment,WBC in the treatment group was higher than that in the control group（P〈0.05）.After three weeks of treatment,there were no significant differences being found in the levels of Hb and BPC in the control group before and after treatment（P〉0.05）.Levels of Hb and BPC in the treatment group were increased when compared with those before treatment（P〈0.05）,which were increased when compared with those in the control group（P〈0.05）.After treatment,the total effective rate was 91.9% in the treatment group and 69.4%in the control group,difference being significant（P〈0.05）.The improvement rate of quality of life was 94.6% in the treatment group and 63.9% in the control group,difference being significant（P〈0.05）.Conclusion：The therapy of Shengbai tang combined with deep thermotherapy has an effect on improving myelosuppression after chemotherapy,can obviously increase the levels of WBC,Hb and BPC,and promote the clinical effect and improve quality of life.