雷氏补火生土法配合脐疗治疗腹泻型肠易激综合征临床研究

Clinical Study on Lei's Method of Supplement Fire to Generate Earth Combined with Umbilical Therapy for Diarrhea-predominant Irritable Bowel Syndrome

目的:观察雷氏补火生土法配合脐疗治疗腹泻型肠易激综合征(IBS-D)脾肾阳虚证的临床疗效。方法:选取60例IBS-D脾肾阳虚证患者,随机分为试验组和对照组各30例。试验组采用雷氏补火生土法配合脐疗治疗,对照组采用常规西药治疗,2组疗程均为4周。治疗后比较2组临床疗效,观察患者中医症状及生活质量的改善情况。结果:试验组总有效率89.7%,对照组总有效率66.7%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组中医症状积分、IBS症状严重程度量表(IBSSSS)及IBS生活质量量表(IBS-QOL)评分比较,差异均无统计学意义(P>0.05)。治疗后,2组中医症状积分、IBS-SSS及IBS-QOL评分均较治疗前下降,差异均有统计学意义(P<0.05);试验组以上3项评分均低于对照组,差异均有统计学意义(P<0.05)。治疗期间,2组均未发生明显不良反应。结论:雷氏补火生土法配合脐疗治疗IBS-D脾肾阳虚证疗效显著,可有效改善患者的临床症状和提高生活质量,且用药安全。

Objective：To observe the clinical effect of Lei＇s method of supplement fire to generate earth combined with umbilical therapy for diarrhea-predominant irritable bowel syndrome（IBS-D）with yang deficiency of spleen and kidney syndrome.Methods：Selected 60 cases of IBS-D patients with yang deficiency of spleen and kidney syndrome,and divided them into the experiment group and the control group randomly,30 cases in each group.The experiment group received Lei＇s method of supplement fire to generate earth combined with umbilical therapy for treatment,while the control group received routine western medicine.The treatment of the two groups lasted for four weeks.After treatment,compared the clinical effect and observed the improvement of Chinese medicine symptoms and quality of life of patients in the two groups.Results：After treatment,the total effective rate was 89.7% in the experiment group and was 66.7% in the control group,difference being significant（P〈0.05）.Before treatment,no significant difference was found in the comparisons of sores of Chinese medicine symptoms,IBS symptom severity scale（IBS-SSS）and IBS quality of life（IBS-QOL） between the two groups（P〉0.05）.After treatment,sores of Chinese medicine symptoms,IBS-SSS and IBS-QOL in the two groups were all decreased when compared with those before treatment,differences being significant（P〈0.05）.The above three scores in the experiment group were lower than those in the control group,differences being significant（P〈0.05）.During the treatment,no obvious adverse reaction was found in both groups.Conclusion：The therapy of Lei＇s method of supplement fire to generate earth combined with umbilical therapy has significant curative effect in treating IBS-D with yang deficiency of spleen and kidney syndrome,which can effectively improve clinical symptoms and quality of life of patients with safe medication.