鲍曼不动杆菌耐药机制及感染控制的研究进展

Research progress of resistant mechanism and the infection control of Acinetobacter baumannii

鲍曼不动杆菌是一种重要的革兰阴性条件致病菌,具有极强环境适应能力和获得外源性耐药基因的能力,易引起院内感染暴发流行。近年来,多重耐药和泛耐药鲍曼不动杆菌引起的医院感染逐年增加,病死率极高,因此他们被称为21世纪革兰阴性杆菌中的"耐甲氧西林金黄色葡萄球菌(MRSA)"。笔者就多重耐药鲍曼不动杆菌耐药、耐药机制及其控制的研究进展作一综述。

Acinetobacter baumannii is an important gram-negative opportunistic pathogens with a strong environmental adaptation to obtain exogenous resistant gene,which is easy to form a biomembrane and cause outbroke nosocomial infection. In recent years,multi-drug resistant Acinetobacter baumannii and Pandrug-resistant Acinetobacter baumannii caused the hospital infections increasingly year by year and leads to higher mortality.Acinetobacter baumannii was called ＂Methicillin-resistant Staphylococcus aureus（ MRSA） ＂of gram-negative bacilli in 21 century.In this paper,the mechanism and control of multidrugresistant Acinetobacter baumannii is reviewed in this paper.