维持性血液透析患者腹主动脉钙化与血清铁蛋白相关性分析

Correlation Between Abdominal Aorta Calcification and Serum Ferritin Level in Maintenance Hemodialysis Patients

目的探讨维持性血液透析患者血清铁蛋白与血管钙化的关系。方法利用腹部侧位x线片评估腹主动脉钙化积分，将80例维持性血液透析患者分为血管钙化阴性组、轻度血管钙化组、中度血管钙化组和重度血管钙化组，分析腹主动脉钙化积分与血清铁蛋白水平之间的关系。结果维持性血液透析患者血清铁蛋自水平增加的同时，腹主动脉钙化严重程度加重。多组间两两比较差异均有统计学意义，Spearman相关分析发现腹主动脉钙化与血清铁蛋白水平呈正相关性（r=0．512，P〈0．01）。结论血清铁蛋白水平升高可能加重维持性血液透析患者血管钙化。

Objective To observe correlation between abdominal aorta calcification （AAC） and serum ferritin in maintenance hemodialysis （MHD） patients. Methods According to abdominal aorta calcification score （AACs）, a total of 80 patients with MHD were divided into calcification negative group, mild calcification group, moderate calcification group and severe calcification group. The correlation between AAC and serum ferritin was analyzed. Results Along with the serum ferritin levels increased, AAC was aggravated. There were significant differences among the four groups. Spearman correlation coefficient showed a positive correlation between serum ferritin levels and AAC scores in MHD patients （r=0.512, P 〈 0.01）. Conclusion Elevated serum ferritin might aggravate vascular calcification in MHD patients.