基于Citespace进行超重或肥胖儿童青少年胰岛素抵抗研究的可视化分析

Visualization analysis of insulin resistance in overweight or obesity in children and adolescents based on citespace

目的应用CitespaceⅤ软件对相关文献进行可视化分析,以探索超重或肥胖儿童青少年胰岛素抵抗研究的热点。方法以Web of Science核心杂志为数据库来源,检索出超重或肥胖儿童青少年胰岛素抵抗主题相关的文献,利用CitespaceⅤ软件,对2 587篇文献所在国家或地区、关键词和被引文献等进行可视化分析和解读。结果可视化分析显示,美国在肥胖儿童胰岛素抵抗领域的发文量最多,其国内各大机构间的密切合作有利于该领域的发展并取得更多的研究成果。关键词的前几大聚类的标签名主要涉及代谢综合征、胰岛素抵抗、非酒精性脂肪肝(NAFLD)、运动等内容,心血管疾病(CVD)及NAFLD是近年来研究的热点。结论 CitespaceⅤ软件的可视化分析功能,有助于了解超重或肥胖儿童青少年胰岛素抵抗研究的区域、热点和主要关注的问题,为进一步研究肥胖相关并发症的病理机制、预防和治疗提供依据。

Objective To explore the research hot spots of insulin resistance in overweight or obesity in children and adolescents globally. Methods Related articles were searched from Web of Science core journals based on the theme of ＂insulin resistance in overweight or obese children and adolescents＂,and finally 2 587 articles were retrieved.Countries,research institutions,keywords and cited references from the 2 587 articles were analyzed by the visualization software CitespaceⅤ. Results Visualization analysis indicated that most of the articles in this field were from U.S.A.The close cooperation among different institutions was beneficial to develop the field and get more achievements.The analysis of keywords showed that the top clusters mainly focus on metabolic syndrome,insulin resistance,non-alcoholic fatty liver disease,physical and so on.Cardiovascular disease and NAFLD were the hottest spots during the recent years. Conclusions The visualization analysis contributes to realize that the region,hot spots and the problems regarding the insulin resistance in overweight or obesety in children and adolescents,thereby providing the evidence for pathophysiologic mechanism,prevention and treatments of obesity comorbidities.