妊娠晚期妇女B族链球菌感染危险因素分析

Analysis on risk factors of B group streptococcal infection in third trimester pregnant women

目的回顾性分析温州市妊娠晚期妇女感染B族链球菌(GBS)的相关危险因素,为妊娠期人群做好GBS早期干预治疗提供依据。方法选取2016年6月-12月在某医院进行常规产检妊娠晚期妇女,采集阴道和直肠分泌物标本。采用培养法测定阴道和直肠分泌物标本中GBS,并通过检查阴道分泌物了解有无外阴阴道念珠菌病;同时收集受检孕妇的年龄、体重指数、妊娠并发症、孕产史、既往分娩方式和妊娠晚期性生活等相关信息。评价妊娠晚期GBS感染情况,分析GBS感染危险因素。结果 2 235份阴道和直肠分泌物标本中,有114例GBS阳性,阳性率为5.10%;高体重指数、合并有妊娠期外阴阴道念珠菌病(VVC)、妊娠期糖尿病、有流产史、阴道分娩史、妊娠晚期性生活史的孕妇GBS阳性率高于对照组。结论妊娠晚期妇女B族链球菌感染的危险因素包括高体重指数、妊娠期糖尿病、VVC、流产史、阴道分娩史、妊娠晚期性生活等,需要有针对性地采取预防措施控制感染率。

Objective To analysis on the factors related to B group Streptococcal（ GBS） infection in third trimester pregnant women in Wenzhou city retrospective,and provide the basis for early intervention treatment of GBS in pregnant people.Methods Third trimester pregnant women were selected from a hospital from Jun to Dec 2016,and samples of vaginal and rectal secretions were collected. GBS in vaginal and rectal secretions was measured by culture method and the presence of candidal vaginitis was examined by examining vaginal secretions. At the same time,we collected information about the pregnant women＇s age,body mass index,pregnancy complications,pregnancy history,previous birth,sexual life in third trimester to evaluate the infection status of GBS in third trimester and analyze the risk factors of GBS infection. Results Of the 2 235 samples of vaginal and rectal secretions,114 were GBS positive,with a positive rate of 5. 10%. The positive rate of GBS in pregnant women who had high body mass index or combined with vulvovaginal candidiasis（ VVC）,gestational diabetes,abortion history,vaginal delivery history,sexual life in third trimester was higher than that of the control group. Conclusion The risk factors for B Streptococcal infection in third trimester include high body mass index,gestational diabetes mellitus,VVC,previous vaginal delivery,and sexual life in third trimester. We should adopt targeted prevention measure to control infection rate.