超声强化苯甲醇合成苯甲醛的研究

Study on ultrasound-enhanced synthesis of benzaldehyde from benzyl alcohol

以苯甲醇为原料,次氯酸钠溶液为氧化剂,四丁基溴化铵为相转移催化剂,利用超声强化苯甲醇合成苯甲醛。考察了反应溶剂、反应时间、催化剂用量对反应的影响。最佳反应条件是:以乙酸乙酯为溶剂,反应时间为2 h,催化剂与原料摩尔比为0.15。同时探讨了在超声辅助下,超声功率、反应时间、催化剂用量对反应的影响。结果表明,在超声功率为500 W、反应时间为15 min、催化剂与原料摩尔比为0.1时,反应收率为92.6%。从对比实验结果可知,超声可以极大地强化反应的进行。

Benzaldehyde is synthesized with ultrasound-enhanced method by using benzyl alcohol as raw material,sodium hypochlorite solution as oxidant and tetrabutyl ammonium bromide as phase transfer catalyst. The effects of solvent,reaction time and dosage amount of catalyst on the reaction are explored.The optimum reaction conditions are as follows： ethyl acetate is used as solvent,reaction time is 2 h and the molar ratio of catalyst to raw material is 0. 15. The effects of ultrasonic power,reaction time and dosage amount of catalyst on the reaction under ultrasound-assisted conditions are explored.It is found that the yield of the reaction can reach 92. 6% when the ultrasonic power is 500 w,the reaction lasts for 15 min and the molar ratio of catalyst to raw material is 0. 1.It is known from the contrast experiments that ultrasound can greatly enhance the reaction.