氟哌噻吨美利曲辛联合匹维溴胺治疗腹痛型肠易激综合征的疗效观察

The clinical effect observation of flupenthixol melitracen combined with pinaveriumbromide in treatment of abdominal pain irritable bowel syndrome

目的观察氟哌噻吨美利曲辛联合匹维溴胺治疗腹痛型肠易激综合征的疗效。方法将120例腹痛型肠易激综合征患者随机分为试验组和对照组各60例。试验组予氟哌噻吨美利曲辛联合匹维溴胺治疗。对照组采用匹维溴胺治疗。对比观察2组患者的临床疗效、疼痛(VAS)和焦虑(SAS)评分。结果试验组治疗总有效率为93.33%高于对照组的68.33%,差异有统计学意义(χ2=5.239,P=0.03,P<0.05)。治疗前2组VAS、SAS评分比较差异无统计学意义(P>0.05),治疗后2组均降低,且试验组低于对照组,差异均有统计学意义(P<0.01)。结论氟哌噻吨美利曲辛联合匹维溴胺治疗腹痛型肠易激综合征效果很好,能较好的改善其腹痛症状,提高治疗效果,值得临床推广应用。

Objective To observe the clinical effect of flupenthixol melitracen combined with pinaveriumbromide in treatment of abdominal pain irritable bowel syndrome. Methods 120 cases patients with abdominal pain irritable bowel syndrome were randomly divided into test group and control group,each of 60 cases. Test group was treated by flupenthixol melitracen combined with pinaveriumbromide. Control group was treated by pinaveriumbromide. After treatment,compared the clinical effect and pain and anxiety scores of 2 group. Results The total efficiency of test group（ 93. 33%） was higher than that of control group（ 68. 33%）,the difference was statistic significantly（ χ2= 5. 239,P = 0. 03,P 〈0. 05）. The VAS,SAS score of 2 group before treatment was no statistic significantly（ P〉 0. 05）. The VAS,SAS score of 2 group after treatment were lower than that before treatment,and the VAS,SAS score of test group after treatment was lower than that of control group,the difference was statistic significantly（ P 〈0. 01）. Conclusion Flupenthixol melitracen combined with pinaveriumbromide in treatment of abdominal pain irritable bowel syndrome has a good effect,can better improve the symptoms of abdominal pain,improve the treatment effect,worthy of clinical application.