职业紧张因素对人体甲状腺功能及肝功能指标的研究

Effects of occupational stress factors on the function of thyroid and liver among petroleum refining and petrochemical workers

目的 探讨石油炼化工人职业紧张因素与甲状腺功能以及肝功能指标浓度水平间的关联.方法 于2016年6月-7月,采用职业紧张目录问卷（OSI-R）对石油炼化工人353人进行问卷调查,并测定其甲状腺功能以及肝功能指标水平.结果 随着任务控制、决策控制、环境控制、资源控制、技术利用程度评分值的增大,TT4浓度水平降低（P＜0.05）,定量负荷、负荷变化、工作危险性、工作前景、提升机会、参与决策评分值的增大,TT4浓度水平升高（P＜0.05）;随着任务控制、决策控制、环境控制、资源控制、定量负荷、负荷变化、提升机会、参与决策评分值的增大,总蛋白浓度水平降低（P＜0.05）,随着技术利用程度、工作危险性、工作单调性、工作前景评分值的增大总蛋白浓度水平升高（P＜0.05）.职业因素评分低、中、高水平组间工作需求、工作控制评分存在统计学差异（P＜0.05）.结论 石油炼化工人职业紧张因素对甲状腺功能以及肝功能指标水平有一定影响.

Objective To investigate the association between occupational stress factors and the level of thyroid function and liver function in petroleum refining and petrochemical workers.Methods A total of 353 petroleum refining workers were investigated by occupational stress indicator question-naire （OSI-R）,and their level of thyroid and liver function were measured.Results With the incre-ase of task control,decision control,environmental control,resource control and technology utilization score,the TT4 concentration level decreased （P〈0.05）.The TT4 concentration level increased with the increase of the quantiontive load,load changes,job hazards,job prospects,promation opportunities and participaction decision rating （P〈0.05）.The total protein concentration level decreased with the increase of task control,decision control,environmental control,resource control,quantitative load,load change,promotion opportunity and participation decision value（P〈0.05）,increased with the use degree of technology,work risk,job monotonous,work prospects score rised（P〈0.05）.And there were statistically significant differences in the job requirements and job control scores between the low,middle and high levels of occupational factors （P〈0.05）.Conclusion Occupational stress factors of petroleum refining workers have certain influence on the level of thyroid and liver function index.