赵氏雷火灸对桥本甲状腺炎患者TGA、MCA的影响

Effect of ZHAO's thunder fire moxibustion on TGA and MCA in patients with Hashimoto's Thyroiditis

目的探讨赵氏雷火灸对桥本甲状腺炎甲状腺功能减退期患者血清抗甲状腺过氧化物酶抗体(TGA)、血清抗甲状腺微粒体抗体(MCA)的影响。方法将60例患者随机分为药物组及灸药组,分别以左甲状腺素钠片口服、左甲状腺素钠片口服配合赵氏雷火灸治疗。治疗周期4周。观察比较治疗前后2组患者血清抗甲状腺过氧化物酶抗体(TGA)、血清抗甲状腺微粒体抗体(MCA)含量。结果治疗4周后,2组治疗后血清TGA水平均较治疗前明显降低,灸药疗组明显低于药疗组(36.23±21.21 VS 47.53±20.11)(P<0.01);2组治疗后血清MCA水平均较治疗前降低(灸药组P<0.01,药物组P<0.05),灸药疗组明显低于药疗组(23.25±11.26 VS35.53±16.29)(P<0.01)。结论赵氏雷火灸疗法可明显降低桥本甲状腺炎甲状腺功能减退期患者血清抗甲状腺过氧化物酶抗体(TGA)、血清抗甲状腺微粒体抗体(MCA)水平。

Objective To observe the efficacy on Hashimoto＇s thyroiditis hypothyroidism treated with Zhao＇s thunder-fire moxibustion, so as to provide the influence of TGA and MCA. Methods Sixty cases of Hashimoto＇s thyroiditis were randomized into Zhao＇s thunder-fire moxibustion and Zhao＇s thunder-fire moxibustion with levothyroxine sodium tablets method. After 4 weeks of treatment cycle. TGA score, and MCA score were observed and compared before and after treatment in the patients between the two groups. Results After the treatment cycle of four weeks, TGA scores were decreased apparently after treatment in the two groups and the Zhao＇s thunder-fire moxibustion with levothyroxine sodium tablets method group were obviously decreased to that in the levothyroxine sodium tablets method group（36.23±21.21 VS 47.53±20.11）（P〈0.01）. MCA scores were decreased apparently after treatment in the two groups.（Zhao＇s thunder-fire moxibustion with levothyroxine sodium tablets method group P〈0.01, the levothyroxine sodium tablets method group P〈0.05）, the Zhao＇s Thunder-Fire moxibustion with levothyroxine sodium tablets method group were obviously decreased to that in the levothyroxine sodium tablets method group（23.25±11.26 VS 35.53±16.29, P〈0.01）. Conclusion The level of serum anti-thyroid peroxidase antibody（TGA） and serum anti-thyroid microsomal antibody（MCA） in patients with Hashimoto＇s thyroiditis at hypothyroidism stage were significantly decreased by Zhao＇s thunder-fire moxibustion therapy.