脉冲振荡肺功能检测在稳定期慢性阻塞性肺疾病诊断中的价值分析

Clinical value of pulsed pulmonary function test in the diagnosis of chronic obstructive pulmonary disease

目的探讨脉冲振荡肺功能检测在稳定期慢性阻塞性肺疾病诊断中的临床价值。方法选择2016年3月至2017年3月海阳市人民医院收治的稳定期慢性阻塞性肺疾病患者32例为观察组及同期健康体检排除慢性阻塞性肺疾病患者32例为对照组，均行脉冲振荡肺功能检测，比较脉冲振荡技术检测相关指标以及肺功能检测指标。结果观察组共振频率、呼吸总阻抗、中心气道阻力及周边气道阻力分别为（16.9±1.5）kPa·L－1·s－1、（0.46±0.03）kPa·L－1·s－1、（0.56±0.05）kPa·L－1·s－1和（0.15±0.03）kPa·L－1·s－1，均高于对照组的（9.5±0.3）kPa·L－1·s－1、（0.26±0.01）kPa·L－1·s－1、（0.24±0.01）kPa·L－1·s－1和（0.02±0.01）kPa·L－1·s－1（t＝30.595、40.000、39.691和26.000，均P〈0.05），观察组第一秒用力呼气容积（FEV1%）为（41.5±1.9）%，低于对照组的（81.1±2.0）%（t＝47.229，P〈0.05），用力肺活量比值（FEV1/FVC）水平为（49.5±3.3），低于对照组的（81.9±2.6）（t＝21.678，P〈0.05）。结论脉冲振荡肺功能检测结果与常规肺功能检查具有同步性与一致性，尤其适用于老年、小儿及危重症患者。

ObjectiveTo investigate the clinical value of pulsed pulmonary function in the diagnosis of chronic obstructive pulmonary disease（COPD）.Methods32 patients with chronic obstructive pulmonary disease admitted to Haiyang People＇s Hospital from March 2016 to March 2017 were selected as observation group.Another 32 cases without COPD were selected as control group.All the patients received pulsed pulmonary function test.The relevant indicators of oscillation technology and pulmonary function test indicators were compared between the two groups.ResultsThe resonance frequency, total respiratory impedance, central airway resistance and peripheral airway resistance in the observation group were （16.9±1.5）kPa ·L-1·s-1, （0.46±0.03）kPa·L-1·s-1, （0.56±0.05）kPa ·L-1·s-1 and （0.15±0.03）kPa ·L-1·s-1, which were significantly higher than those in the control group [（9.5±0.3）kPa·L-1·s-1, （0.26±0.01）kPa ·L-1·s-1, （0.24±0.01）kPa·L-1·s-1, （0.02±0.01）kPao·L-1·s-1] （t=30.595, 40.000, 39.691 and 26.000, all P〈0.05）. The FEV1% in the observation group was （41.5±1.9）%, which was lower than （81.1±2.0）% in the control group（t=47.229, P〈0.05）. The FEV1/FVC level in the observation group was （49.5±3.3）, which was lower than （81.9±2.6） in the control group（t=21.678, P〈0.05）.ConclusionThe results of pulsed pulmonary function are synchronous and consistent with routine pulmonary function test, especially for elderly, pediatric and critically ill patients.