经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的疗效及对患者生活质量的改善效果

Effect of percutaneous kyphoplasty on the quality of life in patients with osteoporotic vertebral compression fractures

目的研究骨质疏松性椎体压缩性骨折患者应用经皮椎体后凸成形术（PKP）的疗效，以及对患者生活质量的影响。方法选择绍兴市上虞区人民医院骨科2014年1月至2016年1月收治的骨质疏松性椎体压缩性骨折患者100例为研究对象，采用随机数字表法将其分为对照组和观察组各50例，对照组采用经皮椎体成形术（PVP）治疗，观察组采用PKP治疗，记录比较两组患者手术前后椎体前缘高度和后凸Cobb角、疼痛程度、肢体功能障碍程度以及生活质量评分。结果手术后，观察组视觉模拟评分法（VAS）和Oswestry功能障碍指数问卷表（ODI）评分分别为（2.27±1.25）分、（27.17±7.35）分，均低于对照组的（3.52±1.57）分、（44.28±8.63）分，差异均有统计学意义（t＝4.404、9.913，均P〈0.05）。手术后，观察组椎体前缘高度为（19.87±1.33）mm，高于对照组的（19.22±1.30）mm；后凸Cobb角为（5.31±2.12）°，小于对照组的（6.34±2.78）°，差异均有统计学意义（t＝2.471、2.083，均P〈0.05）。手术后，观察组生活质量评分为（78.69±13.77）分，高于对照组（65.46±12.67）分，差异有统计学意义（t＝4.999，P〈0.05）。结论采用PKP治疗骨质疏松性椎体压缩性骨折，疗效肯定，恢复椎体前缘高度，并且矫正椎体后凸畸形，能够明显缓解疼痛，改善患者肢体功能，提高患者的生活质量，值得临床推广应用。

ObjectiveTo study the effect of percutaneous kyphoplasty（PKP） in the treatment of patients with osteoporotic vertebral compression fractures（OVCF）, and its influence on the quality of life of patients.Methods100 cases with OVCF from January 2014 to January 2016 in Department of orthopedics, Shangyu District People＇s Hospital of Shaoxing city were selected as the research subjects.According to random number table method, the patients were divided into control group and observation group, with 50 cases in each group.The control group was treated by percutaneous vertebroplasty（PVP）, the observation group was treated by PKP.The anterior vertebral height and kyphosis Cobb angle, the degree of pain, limb dysfunction, and quality of life score were compared between the two groups.ResultsAfter operation, the scores of VAS and ODI in the observation group were （2.27±1.25）points and （27.17±7.35）points, respectively, which were lower than those in the control group [（3.52±1.57）points, （44.28±8.63）points]（t=4.404, 9.913, all P〈0.05）. After operation, the height of the anterior border of the observation group was （19.87±1.33）mm, which was higher than （19.22±1.30）mm of the control group, and the kyphosis Cobb angle of the observation group was （5.31±2.12）°, which was less than （6.34±2.78）°of the control group （t=2.471, 2.083, all P〈0.05）. After operation, the score of quality of life in the observation group was （78.69±13.77）, which was higher than （65.46±12.67） in the control group （t=2.471, 2.083, all P〈0.05）.ConclusionThe curative effect of PKP in the treatment of OVCF is positive, it can restore vertebral height, correct kyphosis, relieve pain, improve limb function of patients, and improve the quality of life of patients, it is worthy of clinical application.