纳迪克酸酐的合成研究

Synthesis Research of Nadic Anhydride

以C5馏分中的环戊二烯为二烯体,顺丁烯二酸酐为亲二烯体,进行Dails-elder反应合成纳迪克酸酐,得到一种较好的外型纳迪克酸酐合成方法。并利用气相色谱-质谱联用法测定产物中外型产物的比率。通过正交试验对原料配比、滴加温度、滴加时间、反应温度、反应时间进行优化,得到最佳工艺条件:n(MA)∶n(CPD)=1.1∶1,滴加时间为4 0 min,滴加温度为2 5℃,反应时间为9 0 min,反应温度为3 5℃,此条件下合成产物的收率为84.79%,外式比例为49.21%。产物采用红外光谱进行了分析。

Using cyclopentadiene as dienes and maleic anhydride as dienes in C5 fraction,a better method for the synthesis of nadidic anhydride is obtained by Dails-elder reaction. Gas chromatography-mass spectrometry（ GC-MS） is used to determine the ratio of the external products in the products. The raw material ratio,dropping temperature and time,reaction temperature and reaction time are optimized by orthogonal test. The optimum process conditions： n（ MA） ∶ n（ CPD） is 1. 1 ∶ 1,the dropping time is 40 min,dropping temperature is 25 ℃,the reaction time is 90 min,the reaction temperature is 35 ℃. The yield of synthetic product under the optimal technological condition is 84. 79%,and the external proportion is 49. 21%. The products are analyzed by infrared spectroscopy.