摘要
羊毛甾烷型三萜是四环三萜类化合物,是多孔菌科真菌中含量较为丰富的一类次级代谢产物。羊毛甾烷型三萜类化合物可以划分为A、B、C、D、E 5种主要骨架构型,具有抗肿瘤、抗炎、抗菌等药理活性。通过查阅国内外文献,对多孔菌科20多种真菌中分离出的161种羊毛甾烷型三萜类成分及药理作用研究进展进行了综述,为羊毛甾烷型三萜类成分的研究及多孔菌科真菌药用资源的合理应用与开发提供参考。
Lanostane-type triterpenoid is a kind of tetracyclic triterpene compound, which belongs to secondary metabolics in fungi of Polyporaceae with abundant content. In the paper, combined with the domestic and foreign literature, the pharmacological activities on the 161 kinds of lanostane-type triterpenoids isolated from more than 20 species of Polyporaceae fungi are summarized. The compounds are divided into A, B, C, D, and E five kinds of main skeleton configurations. Their pharmacological activity researches are mainly concentrated in antitumor, anti-inflammatory, antibacterial and so on. The paper provides reference value for rational use and development of the medicinal resources of the fungi of Polyporaceae and their lanostane-type triterpenoids.
作者
包海鹰
史帧婷
冯爽
BAO Hai-ying;SHI Zhen-ting;FENG Shuang(College of Chinese Medicine Material, Jilin Agricultural University, Changchun 130118, China;Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi, Jilin Agricultural University, Changchun 130118, China)
出处
《中草药》
CAS
CSCD
北大核心
2018年第9期2172-2187,共16页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(31270088)
关键词
真菌
多孔菌科
四环三萜
羊毛甾烷型三萜
抗肿瘤活性
抗炎活性
抗菌活性
fungi
Polyporaceae
tetracyclic triterpene
lanostane-type triterpenoids
antitumor activity
anti-inflammatory activity
antibacterial activity
