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左氧氟沙星与阿莫西林联合依替米星对Hp阳性慢性胃炎患者Hp转阴率及不良反应的影响 被引量:2

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摘要 目的:探讨左氧氟沙星与阿莫西林联合依替米星对幽门螺旋杆菌(Hp)阳性慢性胃炎患者Hp转阴率及不良反应的影响。方法:选取我院收治的Hp阳性慢性胃炎患者96例,以随机数字表法分组,对照组(n=48)给予奥美拉唑、甲硝唑、阿莫西林治疗,观察组(n=48)予以左氧氟沙星、阿莫西林与依替米星联合治疗,14d为1个疗程,均治疗3个疗程。对比两组临床疗效,并观察两组Hp转阴率及不良反应。结果:观察组[95.83%(46/48)]总有效率高于对照组[77.08%(37/48)],差异有统计学意义(P<0.05);观察组[93.75%(45/48)]Hp转阴率高于对照组[75.00%(36/48)],差异有统计学意义(P<0.05);观察组[6.25%(3/48)]不良反应发生率低于对照组[22.92%(11/48)],差异有统计学意义(P<0.05)。结论:采用左氧氟沙星与阿莫西林联合依替米星治疗Hp阳性慢性胃炎,能有效提高Hp转阴率,降低不良反应发生率,疗效显著。
作者 张秋艳
出处 《北方药学》 2018年第7期139-140,共2页 Journal of North Pharmacy
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