摘要
肝癌是世界范围内最常见的恶性肿瘤之一,其发病率和死亡率正在逐年上升,严重威胁着人类的健康。尽管在临床上肝癌是以手术治疗为主,但是其术后五年复发率超70%。因此,采用靶向药物治疗也是肝癌治疗的一种重要手段。本文就近年来肝癌治疗的靶点与相关药物的研究进行综述,拟为肝癌的靶向治疗方法提供参考。
Hepatocellular carcinoma is a common malignant tumor. Its incidence and mortality are increasing year by year, and is a serious threat to human health. Although surgical treatment remains a major choice for hepatocellular carcinoma, the 5 year recurrence rate is over 70%. Therefore, targeted drug therapy very an important for hepatocellular carcinoma. This article reviews the targets and related drugs for hepatocellular carcinoma treatment in recent years, and expects to provide a reference for targeted therapy for hepatocellular carcinoma.
作者
王堃
徐意祥
韩潇
胡学雷
WANG Kun;XU Yi-xiang;HAN Xiao;HU Xue-lei(Changjiang Polytechnic, Wuhan 430074;Wuhan Institute of Technology, Wuhan 430205;School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071)
出处
《中南药学》
CAS
2018年第6期820-829,共10页
Central South Pharmacy
基金
湖北省教育厅科学研究计划指导性项目(项目编号:B2017578)
关键词
肝癌
治疗靶点
药物
hepatocellular carcinoma
treatment target
drug