穴位埋线治疗原发性骨质疏松症的临床研究

Clinical Study of Acupoint Catgut-embedding on Primary Osteoporosis

目的:观察穴位埋线治疗原发性骨质疏松症的临床疗效及对骨代谢标志物的影响。方法:将90例原发性骨质疏松症患者随机分为对照组及治疗组,每组45例。对照组口服碳酸钙D_3及阿伦磷酸钠治疗,治疗组在对照组治疗基础上配合穴位埋线治疗,比较两组治疗前后VAS评分、骨密度、I型胶原羟基端肽β-胶原序列(β-CTX)、骨钙素N端中分子片段(N-MID)、25-羟基维生素D_3(25-(OH)D_3)及两组治疗有效率。结果:治疗后,两组患者VAS评分及β-CTX水平较治疗前降低,治疗组降低程度明显低于对照组(P<0.05);骨密度值、N-MID及25-(OH)D_3水平较治疗前升高,治疗组升高幅度高于对照组(P<0.05);治疗组总有效率优于对照组(P<0.05)。结论:穴位埋线能减轻原发性骨质疏松症患者的疼痛,增强骨密度,改善骨代谢,具有显著的临床疗效。

Objective： To observe the clinical effect of acupoint catgut-embedding on treating primary osteoporosis and the influence of catgut-embedding on bone makers. Methods： The 90 primary osteoporosis patients were randomly divided into treatment and control group, 45 cases in each group. The control group was treated with Calcium Carbonate D3 and alendronate sodium, the treatment group was treated with acupoint catgut-embedding besides the same therapy of the control group. The VAS scores, bone density, β-CTX, N- MID, and 25-（OH）D3 were compared among the two groups before and after treatment, and the effective rate was observed. Results： After treatment, the VAS scores and β-CTX decreased in two groups, this two indicators decreased significantly in treatment group than in control group （P〈0.05）; Bone density, N-MID, and 25- （OH）D3 were improved in two groups after treatment, and the treatment group was higher than in control group （P〈0.05）. The effective rate of treatment group was higher than the control group （P〈0.05）. Conclusions： Acupoint catgut-embedding can relieve pain, increase bone density and improve bone metabolism, showing significant clinical effective for osteoporosis patients.