多排螺旋CT心肌灌注扫描在冠心病缺血心肌中的应用价值

Application Value of Multi Slice Spiral CT Myocardial Perfusion Scan in Ischemic Myocardium of Coronary Heart Disease

本研究为了探讨多排螺旋CT心肌灌注扫描技术在冠心病缺血心肌诊断中的应用价值。选取我院2014年4月至2015年5月收治的22例冠心病患者临床资料设为研究组,另随机选取同期来我院健康体检者中15例作为对照组。均对两组患者行256排螺旋CT静息和多巴酚胺负荷心肌灌注扫描,记录两组受试者静息灌注不同时期和负荷灌注不同时期心肌密度的变化情况。结果显示,研究组静息扫描下灌注启动期、延迟10 s、延迟20 s、延迟30 s的心肌密度值与负荷状态下比较,经统计学处理,差异显著具有统计学意义（p〈0.05）,对照组差异不显著,无统计学意义（p〉0.05）;研究组患者的心肌测量值在静息、负荷状态下与对照组比较,经统计学处理,差异显著,具有统计学意义（p〈0.05）。多排螺旋CT心肌灌注多巴胺丁胺负荷诱导在冠心病缺血心肌诊断中的应用,可以对可逆性心肌灌注异常进行鉴别,了解冠心病缺血心肌活性状态,具有较好的临床应用价值,值得在实践中广泛的应用和推广,为今后临床诊治提供参考和借鉴。

To investigate the application value of multislice spiral CT perfusion scan in the diagnosis of ischemic myocardium in coronary heart disease, the clinical data of 22 patients with coronary heart disease（CHD） treated in our hospital from April 2014 to May 2015 was selected as the study group, and the other 15 health examination persons in our hospital during the same period were selected as control group. The patients in two groups were treated with 256 slice spiral CT resting and dobutamine stress myocardial perfusion scans, and myocardial density changes of two groups in different periods of resting perfusion and loading perfusion were recorded. The results showed that when start-up period was delayed for 10 s, 20 s and 30 s under the condition of resting scan perfusion,the myocardial density of the study group had statisticall y significant difference with that under the loading condition,（p〈0.05）; while the control group had no statistically significant difference（p〉0.05）. When the myocardial measurement values of patients in study group under resting and loading conditions were compared with those of control group, the difference was significant and statistical（p〈0.05）. The application of multi slice spiral CT perfusion dobutamine load inducement in diagnosis of myocardial ischemia of coronary heart disease could identify the abnormality in reversible myocardial perfusion and understa nd the active status of myocardial ischemia in coronary heart disease. It had a good clinical application value and was worthy of wide application and promotion in practice. Meanwhile, it could provide a reference for the clinical diagnosis and treatment in the future.