河南口岸3例输入性登革热实验室鉴定及回顾调查

Laboratory Identification of 3 Imported Dengue Fever Cases Together with Theirretrospective Investigation In Henan Port

目的对2017—2018年3例发热归国人员进行实验室病毒RNA鉴定,确认为输入性登革热,进行回顾性流行病学调查,监测河南口岸输入性疫情发生规律。方法采集3例发热归国人员血清样本,提取核酸进行实验室实时荧光RT-PCR检测,调查境外染疫病史。结果 3例发热归国者的血清样本登革热病毒通用型核酸阳性,病毒核酸分型鉴定均为登革热病毒Ⅱ型;病史调查显示,患者感染登革热的时间、地点与疫区疾病流行期吻合,染疫地分别为斯里兰卡、泰国和越南。随后,对患者进行后续医疗援助,直至疾病康复,无传染性。结论确认3例归国染疫人员均为来自境外疫区的输入性登革热病例,应针对来自疫区短期旅游的归国人员加强输入性登革热疾病监测和健康教育。

Objective 3 fever returnees were undertaken with virus RNA laboratory identification during 2017 to 2018,which identified as imported dengue fever,then to take a retrospective investigate the persons concerned in order to monitor the imported infectious diseases outbreak. Methods The serum samples from 3 fever patients were collected and the nucleic acid was extracted for RT-PCR detection in the laboratory.Then,to investigate the epidemic diseases abroad. Results Those serum samples from 3 fever returnees＇ were identified as virus universal nucleic acid positive,with which viral nucleic acid of dengue virus type Ⅱ of the classification identification. The history of the infectious disease showed that the time and place of dengue infection coincided with the epidemic period in the affected areas,and the epidemic areas were in Sri Lanka,Thailand and Vietnam.Subsequently,follow-up medical assistance to the patients concerned,until being recovery without infectivity.Conclusion The 3 confirmed imported dengue fever caseswere returning from overseas dengue epidemic areas,it suggested that the imported dengue disease surveillance and health education concernedfor short-term tourism returnees from the pestilence area be strengthened.