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SASH1与肿瘤关系的研究进展

Research Progress in the Relationship between SASH1 and Tumors
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摘要 SASH1(SAM-and SH3-domain containing 1)基因自发现以来,被逐渐发现可能具有抑制肿瘤发生发展的功能。目前认为SASH1的基因表达情况与多种肿瘤的生物学行为存在一定相关性。本文就目前SASH1基因与恶性肿瘤发生发展的相关研究进展作一综述。 Since the discovery of SASH1 gene,it＇s function of inhibiting tumorigenesis and tumor development has been gradually proved. SASH1 gene is thought to be involved in the biological behaviors of multiple tumors. In this paper,we will review the molecular structure and function of SASH1 gene,as well as its relationship with tumors.
作者 胥博闻 奎翔 王燕 Xu Bowen;Kui Xiang;Wang Yan(Department of Pathology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101 , Yunnan, China)
机构地区 昆明医科大学附属第二医院病理科
出处 《肿瘤预防与治疗》 2018年第3期213-218,共6页 Journal of Cancer Control And Treatment
关键词 SASH1 肿瘤 上皮细胞间充质转化 细胞凋亡 甲基化 基因融合 SASH1 Tumor Epithelial-mesenchymal transition （EMT） Apoptosis DNA methylation Gene fusion
分类号 R730.231 [医药卫生—肿瘤]
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肿瘤预防与治疗
2018年 第3期

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