摘要
目的探讨三七总皂苷联合阿司匹林治疗脑梗死的临床疗效。方法以2015年8月—2017年10月治疗的脑梗死患者120例为研究对象,并随机分为的治疗组和对照组各60例。治疗组采用三七总皂苷与阿司匹林联合治疗,对照组仅采用阿司匹林进行治疗,对比2组的治疗效果、血小板聚集率、复发率以及并发症发生率。结果治疗组的总有效率86.67%(52/60)明显高于对照组71.67%(43/60)(P<0.05)。治疗后治疗组患者的NIHSS量表评分明显低于对照组,血小板聚集率明显低于对照组,复发率明显低于对照组,并发症发生率也明显低于对照组(P<0.05)。结论三七总皂苷联合阿司匹林可起到一定的预防作用,治疗脑梗死效果显著,安全性较高,值得推广。
Objective To study the clinical curative effect of notoginseng total saponins in combination with aspirin in treating cerebral infarction. Methods From August 2015 to October 2017 in our hospital, 120 cases of cerebral infarction patients were selected as the research objects. They were randomly divided into treatment group and control group, with 60 cases in each group. The treatment group was treated with notoginseng total saponin and aspirin combination therapy, and the control group was treated with aspirin only.The therapeutic effect of two kinds of treatments, platelet aggregation rate, recurrence rate and complication rates was compared between the two groups. Results The total effective rate of the treatment group(87.67%, 5/60) was obviously higher than that of the control group(71.67%, 43/60). The NIHSS scale score of the treatment group was significantly lower than that of the control group,platelet aggregation rate of the treatment group was significantly lower than that of the control group, the recurrence rate obviously of the treatment group was lower than that of the control group, and the incidence of complications of the treatment group was significantly lower than the control group( P 〈0.05). Conclusion The notoginseng total saponin in combination with aspirin has certain prevention function, in the treatment of cerebral infarction has remarkable effect and high security, and is worth promoting.
作者
陈丽
陈少贤
杨敏
刘邦德
孙盛同
CHEN Li;CHEN Shaoxian;YANG Min;LIU Bangde;SUN Shengtong(Department of Pharmacy, Baiyun Distrct People's Hospital, Guangdong Province, Guangzhou 510500, China;Department of Pharmacy, Guangdong Province People's Hospital, Guangdong Province, Guangzhou 510080, China)
出处
《中国中医药现代远程教育》
2018年第10期54-56,共3页
Chinese Medicine Modern Distance Education of China
关键词
三七总皂苷
阿司匹林
脑梗死
中风
notoginseng total saponin
aspirin
cerebral infarction
stroke