摘要
自身免疫性肝病(AILD)以循环中出现自身抗体、肝组织学炎症表现和血清免疫球蛋白水平升高为特点,主要包括自身免疫性肝炎(AIH)、原发性胆汁性胆管炎(PBC)、原发性硬化性胆管炎(PSC)、IgG4相关硬化性胆管炎(IgG4-SC)和重叠综合征。早期诊断和早期治疗可显著改善患者预后,提高生活质量。本文将重点评述我国AILD研究中取得的进展和遇到的难点问题。
Autoimmune liver diseases（ AILDs）,including mainly autoimmune hepatitis（ AIH）,primary biliary cholangitis（ PBC）,primary sclerosing cholangitis（ PSC）,IgG4-related sclerosing cholangitis（ IgG4-SC）,and overlap syndromes,are characterized by circulating autoantibodies,inflammatory liver histology,and increased level of serum immunoglobulins. Early diagnosis and management can significantly improve the prognosis of patients and their quality of life. This editorial focused on the research progress and difficulties encountered in studies on AILDs in China.
作者
王绮夏
邱德凯
马雄
WANG Qixia, QIU Dekai, MA Xiong.(Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University; Shanghai Institute of Digestive Disease, Shanghai （200001）)
出处
《胃肠病学》
2018年第5期257-260,共4页
Chinese Journal of Gastroenterology
基金
国家自然科学基金国际合作与交流项目(81620108002)
国家自然科学基金面上项目(81771732
81570511
81770564)
上海市卫生计生系统优秀青年医学人才培养计划(2017YQ037)
上海市青年科技启明星计划(18QA1402700)
