自身免疫性肝病重叠综合征诊治进展

Advances in Diagnosis and Treatment of Autoimmune Liver Diseases Overlap Syndrome

自身免疫性肝病包括自身免疫性肝炎(AIH)、原发性胆汁性胆管炎(PBC)、原发性硬化性胆管炎(PSC)等。同时存在AIH、PBC或PSC特征者称为重叠综合征,若不及时接受治疗常可迅速进展至肝硬化和肝功能衰竭。早期诊断和治疗可显著改善预后。本文就近年自身免疫性肝病重叠综合征的诊治进展作一阐述。

Autoimmune liver diseases include autoimmune hepatitis（ AIH）,primary biliary cholangitis（ PBC）,primary sclerosing cholangitis（ PSC） and so on. The simultaneous presence of features of AIH,PBC or PSC called overlap syndrome,usually has a progressive course toward cirrhosis and liver failure if without prompt management. Early diagnosis and treatment can significantly improve the prognosis. This article summarized the advances in diagnosis and treatment of autoimmune liver diseases overlap syndrome in recent years.