血清降钙素原测定在腹腔感染患者中的应用

Application of Procalcitonin in Patients With Abdominal Infection

目的探讨血清降钙素原(PCT)水平与腹腔感染的关系。方法将65例腹腔感染患者分为严重感染组和一般感染组,计算入院24 h内APACHEⅡ评分,检测血清PCT水平。结果一般感染组30例,PCT为(13.28±7.13)ng/ml,严重感染组35例,PCT为(72.81±18.12)ng/ml。严重感染组PCT水平明显高于一般感染组(P<0.05),严重感染组患者血清PCT水平与APACHEⅡ评分呈正相关(r=0.711,P<0.05);死亡3例,PCT均>100 ng/ml。结论对于严重腹腔感染患者,降钙素原能够较好反映患者病情严重程度及预后。

Objective To explore the relationship between the serum levels of procalcitonin and abdominal infection.Methods 65 patients defined as abdominal infection were assigned into severe infection and general infection groups, APACHE-Ⅱ score and the serum levels of PCT（procalcitonin） of the patients were detected and compared. Results The general infection group including 30 cases, the average value of PCT was（13.28±7.13）ng/ml. The severe infection group including 35 cases, the average value of PCT was（72.81±18.12） ng/ml. The average value of PCT in the severe infection group was significantly higher than that in the general infection group（P 〈 0.05）.The serum levels of PCT in patients with severe infection were positively correlated with APACHE-Ⅱ score（r =0.711, P 〈 0.05）; 3 cases died who all had a PCT value more than 100 ng/ml. Conclusion Serum PCT can be used as an important indicator of the severity of the disease and prognosis.