阿奇霉素治疗盆腔炎的效果观察与评估

Observation on and Evaluation of the Effect of Azithromycin in the Treatment of Pelvic Inflammation

目的探讨阿奇霉素治疗盆腔炎的效果。方法选取我院2014年1月—2016年12月收治的40例盆腔炎患者作为研究对象。并将所有患者随机分为两组。对照组采用五水头孢唑林钠进行治疗,阿奇霉素组则给予阿奇霉素治疗。比较两组盆腔炎治疗总有效率;临床症状消失时间;干预前后患者生活质量。结果阿奇霉素组盆腔炎治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。对照组显效、有效和无效各有10例、5例和5例,总有效率75%;阿奇霉素组显效、有效和无效各有17例、3例和0例,总有效率100%。阿奇霉素组临床症状消失时间为(5.51±1.25)d,短于对照组的(7.46±1.51)d,差异具有统计学意义(P<0.05)。干预前,两组生活质量评分比较,差异不具有统计学意义(P>0.05);干预后,阿奇霉素组生活质量高于对照组,差异具有统计学意义(P<0.05)。结论阿奇霉素治疗盆腔炎的效果确切,可有效降低生活质量,缩短症状消失时间,促进细菌学转阴,在盆腔炎治疗中应用价值高,是理想的治疗药物之一。

Objective To investigate the effect of azithromycin in thetreatment of pelvic inflammation. Methods 40 cases of patients withpelvic inflammatory disease admitted in our hospital from January 2014 to December 2016 were selected as the research subjects. All patientswere randomly divided into two groups. The control group was treatedwith five water cefazolin sodium. The azithromycin group was treatedwith azithromycin. The total effective rate of the two groups of pelvicinflammatory disease, the time of clinical symptom disappearance, andthe quality of life before and after intervention were compared. ResultsThe total effective rate of azithromycin group was higher than that of thecontrol group, and the difference was statistically significant （P 〈 0.05）.The effective, effective and ineffective control group had 10 cases, 5 casesand 5 cases, with a total effective rate of 75%. There were 17 cases, 3 casesand 0 case of azithromycin effective, effective and ineffective, and the totaleffective rate was 100%. The time of clinical symptom disappearance inazithromycin group was （5.51±1.25） d, shorter than that in the control group（7.46±1.51） d, the difference was statistically significant （P 〈 0.05）. Beforeintervention, there was no significant difference in the score of quality oflife between the two groups （P 〉 0.05）. After the intervention, the quality oflife in azithromycin group was higher than that in the control group, and thedifference was statistically significant （P 〈 0.05）. Conclusion Azithromycinis effective in the treatment of pelvic inflammation. It can effectively reducethe quality of life, shorten the time of disappearance of symptoms, promotebacteriology to turn negative, and is of high value in the treatment of pelvicinflammation. It is one of the ideal therapeutic drugs.