妊娠高血压综合征采用硫酸镁和硫酸镁联合硝苯地平的疗效比较

Comparison of the Efficacy of Magnesium Sulfate and Magnesium Sulfate Combined With Nifedipine in the Treatment of Pregnancyinduced Hypertension Syndrome

目的研究分析硫酸镁和硫酸镁联合硝苯地平治疗妊娠高血压综合征的效果。方法选取2013年5月—2015年5月我院收治的112例妊娠高血压综合征患者作为研究对象,将其随机分为硫酸镁组和硫酸镁联合硝苯地平组,每组各56例。对比两组患者的临床治疗效果和并发症情况。结果硫酸镁联合硝苯地平组的临床治疗有效率为98.2%,硫酸镁组的治疗有效率为80.4%,两组对比,差异具有统计学意义(P<0.05)。硫酸镁联合硝苯地平组平均收缩压及平均舒张压均优于硫酸镁组,两组对比,差异具有统计学意义(P<0.05)。结论妊娠高血压综合征临床中可以使用硫酸镁联合硝苯地平治疗,效果突出,并发症几率低。

Objective To study and analyze the effect of magnesium sulfate and magnesium sulfate combined with nifedipine in the treatment of pregnancy induced hypertension. Methods 112 cases of pregnancy induced hypertension in our hospital from May 2013 to may 2015 were selected as research subjects. They were randomly divided into magnesium sulfate group and magnesium sulfate combined nifedipine group, 56 cases in each group. The clinical efficacy and complications of the two groups were compared. Results The effective rate of magnesium sulfate combined with nifedipine was 98.2%, and the effective rate of the magnesium sulfate group was 80.4%. The difference between the two groups was statistically significant（P〈0.05）. The mean systolic blood pressure and mean diastolic blood pressure of magnesium sulfate combined with nifedipine group were better than those of magnesium sulfate group. The difference between the two groups was statistically significant（P〈0.05）. Conclusion Magnesium sulfate combined with nifedipine can be used in the treatment of pregnancy induced hypertension. The effect is prominent, the risk of complications is low.