3-乙基-2-乙酰吡嗪缩4-苯基氨基脲Ag(Ⅰ)配合物的合成、结构和DNA结合性质（英文）

Synthesis,Crystal Structure and DNA-Binding Property of Ag(Ⅰ) Complex with1-(3-Ethylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide

合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Ag_2(HL)(NO_3)_2]_n(1)的结构(HL为3-乙基-2-乙酰吡嗪缩4-苯基氨基脲)。单晶衍射结果表明,配合物1中,HL作为中性四齿配体连接2个Ag(Ⅰ)中心,其中一个Ag(Ⅰ)中心与HL配体中的ON_2供体(羰基O,亚胺N和吡嗪N1原子)和2个单齿硝酸根配位,构成扭曲的四方锥配位构型;而另一个Ag(Ⅰ)离子与1个单齿硝酸根,1个双齿硝酸根和HL配体中的吡嗪N_4原子配位,形成扭曲平面正方形配位构型。另外,相邻的Ag(Ⅰ)离子通过桥联的硝酸根离子相互连接形成二维层状结构;此外,配合物1与DNA的相互作用强于配体。

The title complex [Ag2（HL）（NO3）2]n（1）（HL =1-（3-ethylpyrazin-2-yl）ethylidene-4-phenylsemicarbazide）has been synthesized and characterized by single crystal X-ray diffraction, elemental analysis and IR spectroscopy. X-ray diffraction analysis results show that in 1, HL acts as a neutral tetradentate ligand to connect with two Ag（Ⅰ） centers, one of which adopts a distorted square pyramid coordination geometry involving one HL ligand with ON2 donor set（carbonyl O, imine N, and pyrazine N1 atoms） and two monodentate nitrate anions; while the other one is four-coordinated with one monodentate nitrate anion, one bidentate nitrate anion and pyrazine N4 atom, thus giving a planar square coordination geometry. Adjacent Ag （Ⅰ） ions are further connected by bridged nitrate anions to form a 2D framework; Moreover, the fluorescence spectra indicate that the interaction of the complex 1 with DNA is stronger than that of the ligand HL.