糖尿病合并肺结核患者中血糖控制的价值探讨

Value of Blood Glucose Control in Diabetic Patients with Pulmonary Tuberculosis

目的:探讨糖尿病合并肺结核患者治疗中进行血糖控制的临床治疗价值。方法:回顾性分析某院2016年1月~2017年7月期间住院的96例2型糖尿病合并肺结核初治患者,按照治疗3月时血糖控制的情况分为严格控制组(糖化血红蛋白≤6.5%)、良好组(6.5%<糖化血红蛋白≤7%)和不佳组(糖化血红蛋白>7%),观察不同组间临床治疗效果。结果:严格控制组及良好组痰菌阴性率、肺部病灶吸收情况优于不佳组,其数据对比差异有统计学意义(P<0.05);严格控制组痰菌阴性率、肺部病灶吸收情况较良好组差异无统计学意义(P>0.05);严格控制组低血糖发生率高于良好组,差异有统计学意义(P<0.05)。结论:2型糖尿病合并肺结核患者血糖控制目标建议参照糖化血红蛋白≤7%,是否需要更加严格控制需根据患者年龄、病程及并发症情况综合判断。

Objective：To explore the clinical value of blood glucose control in diabetic patients with pulmonary tuberculosis.Methods：96 cases of patients with type 2 diabetes complicated with pulmonary tuberculosis in a hospital from January 2016 to July 2017 were retrospectively analyzed.According to the condition of blood glucose control at 3 months after treatment,the patients were divided into strict control group（glycosylated hemoglobin≤6.5%）,good control group（6.5% glycosylated hemoglobin≤7%）,and poor group（glycosylated hemoglobin7%）,then the effects of clinical treatment in the three groups were observed.Results：The negative rate of sputum bacteria and the absorption of pulmonary focus in the strict control group and the good group were better than those in the poor group,and the difference was statistically significant（P〈0.05）.The negative rate of sputum bacteria in thestrict control group was not significantly different from that in the good group,with no statistical significance（P〉0.05）.The incidence of hypoglycemia in the strict control group was higher than that in the good control group（P〈0.05）.Conclusion：The target of blood glucose control for patients with type 2 diabetes combined with pulmonary tuberculosis is recommended to refer to glycosylated hemoglobin（HbA1 c）less than 7%.The need for more stringent control should be based on the patient＇s age,course of disease and complications.