硒酵母辅助优甲乐治疗桥本甲状腺炎功能减退疗效

Efficacy of Selenium Yeast Assisted Euthyroxide in the Treatment of Hashimoto's Hypothyroidism

目的:评价桥本甲状腺炎功能减退患者行硒酵母辅助优甲乐治疗的效果,评定临床价值。方法:选入2015年3月~2016年3月某院所收治的桥本甲状腺炎功能减退患者382例,随机分为研究组和参照组,每组191例。参照组患者行基础治疗法,研究组患者行硒酵母辅助优甲乐治疗,对比两组患者治疗前后的甲状腺功能指标以及血清甲状腺自身抗体水平变化。结果:研究组经过治疗后,其F3、F4水平显著优于参照组患者,参照组患者的TSH指标高于研究组,对比差异性存在(P<0.05)。结论:将硒酵母辅助优甲乐的疗法应用于临床对桥本甲状腺炎功能减退病症的治疗中,能够有效控制病情。

Objective：To evaluate the efficacy and clinical value of selenium yeast assisted euthyroid therapy in patients with hashimoto＇s hypothyroidism.Methods：382 patients with hashimoto＇s hypothyroidism treated in a hospital from March 2015 to March 2016 were selected and randomly divided into the study group and the reference group,with 191 cases in each group.The patients in the control group were treated with basic therapy and the patients in the study group were treated with selenium yeast assisted euthyroid therapy.The changes of thyroid function indexes and serum thyroid autoantibodies were compared between the two groups before and after treatment.Results：After treatment,the F3 and F4 levels of the patients in the study group were significantly better than those in the reference group,and the TSH index in the reference group was higher than that in the study group,with significant difference（P 0.05）.Conclusion：The selenium yeast assisted euthyroid therapy in patients with hashimoto＇s hypothyroidism can effectively control the condition.