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心肌标志物定量检测在急性心肌梗死早期诊断中的价值 被引量:1

Quantitative Detection of Myocardial Markers in the Early Diagnosis of Acute Myocardial Infarction
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摘要 目的探讨心肌标志物CTnI、CK-MB与Mb定量检测在急性心肌梗死早期诊断中的临床价值。方法选取在院前疑似心肌梗死的患者68例作为研究对象,对所有患者用定量检测的方法进行心肌标志物CTnI、CK-MB与Mb的检查,将患者最终的检查结果与正常对照组指标进行比较。结果将最终的检查结果与正常对照组指标进行比较,可见用定量检测进行心肌标志物CTnI、CK-MB与Mb的检查,三个指标与正常对照组有明显差异,具有统计学意义(P<0.05)。结论在急性心肌梗死的早期诊断中,通过定量检测心肌标志物CTnI、CK-MB与Mb,不仅准确性高,而且所耗时间短,大大缩短了整个诊断的时长,值得在临床诊断过程中进行推广和应用。 Objective To investigate the clinical value of quantitative detection of myocardial markers CTn I, CK-MB and Mb in the early diagnosis of acute myocardial infarction. Methods A total of 68 patients with prehospital suspected myocardial infarction were selected as the study subjects. CTn I, CK-MB and Mb markers were detected by quantitative detection in all patients. The final examination results were compared with normal controls group. Results The final test results were compared with those of the normal control group. We can see that CTn I, CK-MB and Mb were detected by quantitative detection. There were significant differences between the three indicators of patients and the normal control group, which had statistical significance(P﹤0.05). Conclusion In the early diagnosis of acute myocardial infarction, quantitative detection of CTn I, CK-MB and Mb markers is not only accurate, but also takes a short time, which greatly shortens the duration of the entire diagnosis, and is worthy of being performed during clinical diagnosis. Promotion and application.
作者 王恩 WANG En(Department of Clinical Laboratory, Xuanen County People's Hospital, Enshi Prefecture, Hubei Province, Xuanen Hubei 445500, Chin)
出处 《中国继续医学教育》 2018年第17期46-48,共3页 China Continuing Medical Education
关键词 心肌梗死 诊断方法 心肌标志物 定量检测 CTNI CK-MB MB myocardial infarction diagnosis methods myocardial markers quantitative detection CTnI CK-MB Mb
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  • 1SRUBBS P J, KESSLER A C. Mnlticenter evaluation of the diag- nostic vatients with suspected acute coronary syndromes in routine clinical practice[ J]. Heart, 2003, 89 (3) : 280 - 286.
  • 2NOWAK R M, HUDSON M P. The prognostic significance of seri- al myoglobin tropnin I, and creatine kinase - MB measurements in patients evaluated is the emergency department for acute coronary syndrome[J]. Ann Emerg Med, 2005, 42(3) : 345 -350.
  • 3LEWANDROWSKI K. Point - of - care testing for cardiac markers in acute coronary syndromes and heart failure[ J]. Clin Lab Med, 2009, 29(3): 561 -571.
  • 4Morrow D A, de-Lemos J A, Sabatine M S, et al. Thesearch for a biomarker of cardiac ischemia [ J ]. Clin Chem,2003,49(4): 537.
  • 5Anderson J L, Adams C D,Antman E M, et al. ACCF/AHA focused update incorporated into the ACC/AHA 2007guidelines for the management of patients with unstable angi-na/non-ST- elevation myocardial infarction : a report of theAmerican College of Cardiology Foundation/American HeartAssociation Task Force on Practice Guidelines [ J ]. Circula-tion, 2011,123(18): e426.
  • 6Kushner F G,Hand M, Smith S C Jr, et al. Focused up-dates :ACC/AHA guidelines for the management of patientswith ST-elevation myocardial infarction (updating the 2004guideline and 2007 focused update) and ACC/AHA/SCAIguidelines on percutaneous coronary intervention (updatingthe 2005 guideline and 2007 focused update) : a report of theAmerican Cbllege of Cardiology Foundation/American HeartAssociation Task Force on Practice Guidelines [J]. Circula-tion, 2009,120(22): 2271.
  • 7Kehl D W, Iqbal N, Fard A, et al. Biomarkers in acute my-ocardial injury[J].Transl Res, 2012,159(4): 252.
  • 8Ockner R K, Manning J A, Poppenhausen R B, et al. Abinding protein for fatty acids in cytosol of intestinal mucosa,liver, myocardium, and other tissues [J ]. vScience, 1972,177(43): 56.
  • 9Ozdemir L,Elonu O H, Gocmen A Y. Heart type fatty acidbinding profein is more sensitive than troponin I and creatinekinase myocardial band at early stage in determining myocar-dial injury caused by percutaneous coronary intervention [J ].Int Heart J, 2011, 52(3): 143.
  • 10Garcia-Valdecasas S,Ruiz-Alvarez M J, Garcia De Tena J,et al. Diagnostic and prognostic value of heart-type fatty acid-bindir^ protein in the early hours of acute myocardial inf arc-t.ion[J]. Acta Cardiol, 2011, 66(3) : 315.

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