急性重度有机磷农药中毒致呼吸衰竭患者的临床急诊急救

First Aid Measures for Patients With Respiratory Failure Caused by Acute Severe Organophosphorus Pesticide Poisoning

目的探析急性重度有机磷农药中毒致呼吸衰竭的急救措施及效果。方法选取苏北医院急诊科及重症医学科收治的急性重度有机磷农药中毒致呼吸衰竭的患者44例,行常规治疗的22例患者为常规组,加用呼吸机治疗的22例患者为干预组。观察治疗的效果。结果干预组患者意识恢复时间、自主呼吸恢复时间及CHE活力恢复60%时间均明显短于常规组(P<0.05),SaO_2和PaO_2水平明显高于常规组(P<0.05),PaCO_2和pH值明显低于常规组(P<0.05)。结论在常规治疗基础上加用呼吸机,可促进急性重度有机磷农药中毒致呼吸衰竭患者临床症状的缓解,改善其血气分析水平,效果显著。

Objective To explore the first aid measures and effects of respiratory failure caused by acute severe organophosphorus pesticide poisoning. Methods Forty-four patients with acute respiratory failure caused by acute severe organophosphorus pesticide poisoning were selected from the emergency department and intensive care medicine department of Subei people＇s hospital. Twenty-two patients were treated with conventional therapy as conventional group. Twenty-two patients treated with ventilator were treated as intervention group. The effect of the treatment effect was observed. Results The time of consciousness recovery, recovery time of spontaneous breathing and recovery of CHE activity were significantly shorter in the intervention group than in the conventional group（P﹤0.05）, SaO2 and PaO2 levels were significantly higher than those in the conventional group（P﹤0.05）, PaCO2 and pH values were significantly lower than the conventional group（P﹤0.05）. Conclusion The use of a ventilator on the basis of conventional treatment can promote the relief of clinical symptoms in patients with respiratory failure caused by acute severe organophosphorus pesticide poisoning and improve their blood gas analysis level.