寨卡病毒检测方法的研究进展

Research progress on the detection methods of Zika virus

近几年,寨卡病毒肆虐,在全球范围内引发了大规模的疫情暴发。寨卡病毒感染能引起一些严重的潜在并发症,如新生儿小头症和格林巴利综合症,因此引起了社会的恐慌和全球的广泛关注。由于寨卡病毒的血清学检测容易和其他黄病毒产生交叉反应,故特异有效的检测技术的建立在寨卡病毒疫情防控中极其重要。文章主要对寨卡病毒在全球和中国的流行状况和检测方法包括病原学方法、血清学方法和核酸检测方法的研究进展进行综述,并对其检测方法的研究趋势进行展望。

Zika virus（ ZIKV）,a kind of mosquito borne flavivirus,has spread rapidly in recent years and triggers global large scale epidemic outbreaks. ZIKV infection can lead to severe potential complications such as infant microcephaly and Guillain Barré syndrome,which has caused social panic and global widespread attentions. The serological detection of ZIKV is easy to be confused by other flaviviruses,thus the establishment of specific and effective detection methods is extremely important in the prevention and control of ZIKV transmission. In this paper,the epidemic situation of ZIKV in global and Chinese and research progress of ZIKV detection methods including pathogeny detecting method,serological detecting method and nucleic acid detecting method are reviewed,and the future perspective of detection methods research is also briefly described.