中性粒细胞和淋巴细胞比值与动脉粥样硬化研究进展

Research progress of neutrophil to lymphocyte ratio in atherosclerosis

动脉粥样硬化是心脑血管疾病的共同病理过程,关于动脉粥样硬化发病机制,目前已知的有血栓形成学说、脂质浸润学说、氧化应激学说等9种学说,动脉粥样硬化的炎症机制逐渐走入人们的视线,中性粒细胞和淋巴细胞比值作为有代表性的炎症因子,近来的研究中已被证实为预测冠状动脉疾病预后的重要指标,且在脑血管病领域的研究也逐渐得到关注。文章主要就全血中性粒细胞和淋巴细胞比值与动脉粥样硬化的临床研究进行综述。

Atherosclerosis（ AS） is a common pathological process of cardiovascular and cerebrovascular diseases. There are nine kinds of theories on the atherosclerosis pathogenesis,including lipid invasion theory,oxidative stress theory,etc. In recent years,the inflammatory mechanism of atherosclerosis has grasped more attentions. As representative of the inflammatory factors,neutrophil to lymphocyte ratio（ NLR） has been recently proven as an important prognostic factor of coronary artery disease,and the relative researches in the field of cerebrovascular disease are also focused. This article reviews the clinical research of NLR in atherosclerosis.