摘要
目的探讨5-氨基酮戊酸光动力疗法(ALA-PDT)治疗鼻部日光性角化病(AK)的临床疗效与安全性。方法对我院2014~2017年收治的10例鼻部AK患者进行ALA-PDT治疗并观察疗效及安全性。结果 10例患者共13个鼻部AK皮损,经3次治疗后,12个皮损获得完全缓解(92.3%)、1个皮损部分缓解(7.7%)。治愈患者随访1年均未见复发。结论鼻部AK皮损部位特殊,采用ALA-PDT治疗,疗效确切,复发率低,无瘢痕形成,不良反应轻,值得临床推广。
Objective To evaluate the clinical effect and safety of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) in the treatment of nose actinic keratosis(AK). Methods Ten cases of nose AKpatients in our hospitalfrom2014 to 2017 were treated with ALA-PDT. The curative effect and safety were observed. Reslesions in 10 patients. Twelve lesions achieved complete remission (92.3% ) and only 1 lesion sho(7.7% ). There was no recurrence case during 12 months of follow-up. Conclusions ALA-PDT is with low recurrent rate for the AK lesions on the nose.
作者
韩佳彤
王佩茹
王秀丽
HAN Jia-tong;WANG Pei-ru;WANG Xiu-li(Institute of Photomedicine, Department of DermDisease Hospital,Tongji University School of Medicine,Shanghai 200443, Chin)
出处
《中国眼耳鼻喉科杂志》
2018年第3期175-177,共3页
Chinese Journal of Ophthalmology and Otorhinolaryngology
基金
上海申康医院发展中心临床科技创新项目(SHDC12015123)
上海市科委重点项目子课题(15411950302)
上海市卫生系统优秀青年人才(2017YQ066)