Thioredoxin-1在乳腺癌的表达及临床意义的研究
摘要
乳腺癌是一种严重危害女性生命健康的恶性肿瘤,位于女性肿瘤发病率第一位。近年来,乳腺癌的治疗和诊断取得了很大进展,但复发及预后较差,因此亟需探究乳腺癌的发生、发展机制。硫氧还蛋白-1(Thioredoxin-1)可促进非小细胞肺癌中环氧和酶2的过表达,从而参与肿瘤的发生、发展。
出处
《中国地方病防治》
北大核心
2017年第12期1389-1389,共1页
Chinese Journal of Control of Endemic Diseases
基金
江苏省临床医学科技专项[BL2014071]
二级参考文献4
-
1Arner ES,Holmgren A. The thioredoxin system in cancer[J]. Semin Cancer Biol, 2006,16 (6) : 420-426.
-
2Soslow RA,Dannenberg AJ, Rush D, et al. Cox-2 is expressed in human pulmonary, colonic and mammary tumors[J]. Cancer,2000,89(12) :2637 -2645.
-
3Marks PA. Thioredoxin in cancer-role of histone deacetylase inhibitors[J]. Seminars in Cancer Biology, 2006, 16 (6):436-443.
-
4Noike T, Miwa S, Soeda J, et al. Increased expression of thiore- doxirt-I ,vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer[J]. Hum Pathol, 201)8, 39 (2) :201-208.