摘要
目的:研究银柴胡的化学成分。方法:利用硅胶柱层析、MCI柱层析和反相C18制备液相色谱等手段进行分离纯化,并通过~1H-NMR、^(13)C-NMR等波谱技术进行结构鉴定。结果:从银柴胡乙酸乙酯萃取物中分离得到10个化合物,分别鉴定为:苜蓿素(1)、槲皮素-3-O-β-D-葡萄糖苷(2)、阿福豆苷(3)、鼠李秦素(4)、苜蓿素-7-O-β-D-葡萄糖苷(5)、(-)-丁香酯素(6)、邻苯二甲酸二异丁酯(7)、邻苯二甲酸二丁酯(8)、亚麻酸甲酯(9)、2,3,8-tri-Omethyl ellagic acid(10)。结论:所有化合物均为首次从银柴胡中分离得到。
Objective:To study the chemical, constituents of Stellaria dichotoma var, lanceolata. Methods:The chemical constituents of Stellaria dichotoma vat. lanceolata are isolated by different column chromatographic techniques, including silica gel, MCI and reversed phase C18 prep-HPLC. The structures of these compounds were identified by a comprehensive analysis of the spectroscopic data. Results:Ten con:pounds were isolated from Stellaria dichotoma var. lanceolata. The compounds were identified as tricin ( 1 ) , quercetin-3-O-β-D-glucoside ( 2), afzeloside ( 3 ), rhamnazin ( 4 ), tricin-7-O-β-D-glucopyranoside ( 5 ), ( - ) -syringaresinol ( 6 ), diisobutyl- phthalate ( 7), dibutyl-phthalate ( 8), methyl linolenate ( 9), 2,3,8-tri-O-methyl ellagic acid ( 10).Conclusion: All the compounds are isolated from this plant for the first time.
作者
曹芳
CAO Fang(Pharmacy Department of Yanan University Affiliated Hospital, Yanan 716000, China)
出处
《中药材》
CAS
北大核心
2017年第10期2351-2353,共3页
Journal of Chinese Medicinal Materials
关键词
银柴胡
化学成分
黄酮
Stellaria dichotoma L. var. lanceolata Bge.
Chemical constituents
Flavonoid