腥藤化学成分的研究(Ⅰ)

Studies on Chemical Constituents of Erythropalum scandens(Ⅰ)

目的:研究腥藤的化学成分。方法:采用硅胶柱层析、聚酰胺色谱、反向ODS色谱、MCI色谱、大孔吸附树脂色谱、Sephadex LH-20等色谱和重结晶等方法进行分离和纯化,对分离得到的单体化合物利用理化检验和波谱方法进行结构鉴定。结果:从腥藤药材中分离并鉴定了8个化合物,分别为:壬二酸(1)、正十八烷酸(2)、正丁基-吡喃果糖苷(3)、香草酸(4)、甲基异茜草素-1-甲醚(5)、胡萝卜苷(6)、3-methoxy-4-hydroxyphenylpropane(7)、3,4,5-trimethoxyphenol-1-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside(8)。结论:所有化合物均为首次从该植物中分离得到。

Objective： To study the chemical constituents of Erythropalum scandens. Methods： The chemical constituents was separated and purified by column chromatography and recrystalli zation. The compounds were identified by spectroscopic methods and physicaland chemical properties. Result： Eight compounds were isolated and their tructures were identified as azelaic acid（1）,stearic acid（2）,n-butyl-β-D-fructopyranoside（3）,vanillic acid（4）,rubiadin-1-methyl ether（5）,daucosterol（6）,3-methoxy-4-hydroxyphenylpropane（7）,3,4,5-trimethoxyphenol-1-O-β-D-xylopyranosyl-（1→2）-β-D-glucopyranoside（8）. Conclusion： All the compounds are isolated from this plant for the first time.