体力活动不足、久坐行为与糖代谢异常检出率的关系

Physical Inactivity and Sedentary Behaviors in Relation to Prevalence of Dysglycemia

目的:探讨体力活动(PA)不足和久坐行为(SB)与糖代谢异常检出率的关系。方法:对30~69岁具有至少3项DM危险因素者进行糖耐量筛查,采用国际体力活动问卷(IPAQ-SF)调查PA水平和SB,并利用加速度计对问卷进行效度检验。结果:研究纳入195人,平均年龄(51.92±10.64)岁。糖代谢异常检出率为67.18%,检出率随DM危险因素数量的增多而升高。IPAQ-SF中MPA、MVPA以及SB时间与加速度计测量结果的相关系数r分别为0.35、0.37和0.43。受试者中75.9%属于PA不足,同时具有"PA不足+(年龄≥40岁)+超重/肥胖"三项的受试者最多(48.21%)。在调整了混杂因素之后,与SB≤6h/d组相比,SB>6h/d组受试者的糖耐量异常检出率更高(OR=2.37,95%CI:1.12~5.02)。结论:多种DM危险因素聚集者中糖代谢异常检出率较高,PA不足者较多,SB增加糖代谢异常风险,IPAQ-SF适用于对该人群进行PA评价。建议对糖尿病多危险因素聚集者,尤其是PA不足、SB较多、超重/肥胖者及时筛查并重点关注,降低糖代谢异常发病率。

To explore physical inactivity and sedentary behaviors in relation to prevalence of dysglycemia in multiple risk factor clustering individuals.30~69 years old with three or more risk factors for diabetes screening objects were screened with an OGTT,physical activity and sedentary behavior were evaluated using international physical activity questionnaire（IPAQ-SF）.The validity of IPAQ-SF was evaluated by accelerometer.195 subjects were included in the study（37%men,51.92±10.64 yr）.The prevalence of dysglycemia was 67.18%,new diagnostic type 2 diabetes and prediabetes was23.08% and 44.10% respectively.The detection rate of abnormal glucose metabolism increases with the number of risk factors.Associations between the IPAQ-SF and accelerometer variables were r=0.35,r=0.37,and for r=0.43 for MPA、MVPA and SB.75.9% of the subjects belong to physical inactivity,48.2% of the subjects were in the combination of＂physical inactivity＂and＂age≥40 yr＂and＂overweight/obese＂.After adjusting the confounding factors,the prevalence of dysglycemia was higher among participants ST6 h/d compared with ST≤6 h/d（OR=2.37,95% CI：1.12~5.02）.The prevalence of dysglycemia was higher in the cluster of diabetes risk factors.Physical inactivity and the sedentary behavior were associated with increases the risk of dysglycemia.The IPAQ-SF shows good internal consistency and acceptable validity.It is recommended that people with multiple risk factors of diabetes,especially physical inactivity,sedentary behaviors and overweight people,should be screened and focused on.