健脾补血颗粒辅助治疗小儿缺铁性贫血效果观察

The Clinical Observation of Jianpi Buxue Granules as Adjuvant Therapy for Iron Deficiency Anemia in Children

目的观察健脾补血颗粒辅助治疗小儿缺铁性贫血的临床效果。方法收集2015～2017年东港市中医院收冶的缺铁性贫血患儿102例，随机分为观察组和对照组各51例。给予对照组多维铁口服液；在此基础是，给予观察组小儿健脾补血颗粒，两组均治疗1个月后评价疗效。结果经治疗后，观察组血清铁为（18．6±3．4）μmol／L，对照组为（14.3±2．7）μmol／L，差异有统计学意义（t=3．264，P〈0．05）；观察组不良反应发生率为3．92％，对照组为15．69％，差异有统计学意义（x^2=3．991，P〈0．05）。结论健脾补血颗粒可作为小儿缺铁性贫血治疗的辅助用药，以期提高疗效的同时降低不良反应发生情况。

Objective To observe the clinical effect of Jianpi Buxue Granules as the adjuvant therapy for iron deficiency anemia in children. Methods A total of 102 children with iron deficiency anemia were collected in Donggang Hospital of Traditional Chinese Medicine from 2015 to 2017 and divided into observation group and control group （both 51 cases in each group） randomly. The control group accepted multivitamin iron oral solution, while the observation group accepted Jianpi Buxue Granules based on multivitamin iron oral solution. We compared the curative effects of two groups after a one-month treatment. Results There were significant differences in serum iron between observation group （18.6±3.4 μmol/L） and control group （14.3±2.7 μmol/L）. Moreover, there were significant differences in adverse reaction rate between observation group （3.92%） and control group （15.69%）. Conclusion The Jianpi Buxue Granules could regard as adjunctive medication for iron deficiency anemia in children in order to improve the curative effect and reduce the adverse reactions.