支气管肺发育不良患儿发生急性病毒性下呼吸道感染的预测因素分析

Predictors factor analysis of acute viral lower respiratory tract infection in children with bronchopulmonary dysplasia

目的:探讨支气管肺发育不良(BPD)患儿发生急性病毒性下呼吸道感染(AVLRI)的预测因素分析。方法:回顾性调查2015年6月至2017年6月我院收治的BPD合并AVLRI患儿60例作为合并组,同期选取60例BPD无合并AVLRI患儿作为对照组,分析BPD患儿发生AVLRI的预测因素。结果:本次调查中,合并组以呼吸道合胞病毒(RSV)感染为主,有35例(58.00%);单因素法分析结果显示,BPD患儿发生AVLRI与季节、喂养方式、家庭吸烟和患儿BPD病情、出生体重、合并基础疾病、合并先心病及母体孕期糖尿病、特应性疾病等因素有关(P<0.05);Logistics多因素法分析结果显示,秋冬季节、患儿重度BPD、合并先心病、母体特应性疾病、人工喂养是BPD患儿发生AVLRI的预测因素(P<0.05)。结论:BPD合并AVLRI患儿常因RSV发病,其发生是由多种因素引起,秋冬季节、患儿重度BPD、合并先心病、母体特应性疾病、人工喂养等可能可作为其发生的预测因素,应针对上述因素采取各项有效的干预措施。

Objective：To discuss the predictors factor analysis of acute viral lower respiratory tract infection（AVLRI） in children with bronchopulmonary dysplasia（BPD）.Methods：Retrospective survey 60 patients with BPD complicated with AVLRI were selected from June 2015 and June 2017 in our hospital as a combined group,60 children with BPD without AVLRI were selected as control group at the same time,analysis of predictors of AVLRI in children with BPD.Results：In this survey,combined group with respiratory syncytial virus（RSV） infection was the main type of infection,and there were 35 cases（58%）,the result of single factor analysis showed,the incidence of AVLRI in children with BPD was related to factors such as season,feeding mode,family smoking,BPD condition,birth weight,basic diseases,congenital heart disease,maternal gestational diabetes mellitus,atopic diseases and so on（P〈0.05）,the result of Logistics multivariate factor analysis showed,autumn winter season,severe BPD,congenital heart disease,maternal atopic disease,and artificial feeding were predictors of AVLRI in BPD children（P〈0.05）.Conclusion：BPD complicated with AVLRI is often caused by RSV,it is caused by a variety of factors,autumn is the high incidence season,autumn and winter,children with severe BPD,congenital heart disease,maternal atopic disease and artificial feeding may be as a predictor of the occurrence,the effective measures should be taken according to the above factors.