脑肿瘤患者术后脑脊液感染相关因素分析

Related factors of cerebrospinal fluid infection in patients with brain tumor after operation

目的分析脑肿瘤患者术后发生脑脊液感染的相关因素。方法回顾性分析2016年5月-2017年3月于医院神经外科行脑肿瘤术患者225例的临床资料,分析脑肿瘤术后发生脑脊液感染的相关因素。结果 225例患者中发生脑脊液感染79例,发生率为35.11%,其中死亡2例,其余患者经过治疗后均恢复正常;年龄,肿瘤大小,脑室外引流,颅外感染灶,营养不良,贫血,低蛋白血症,合并糖尿病是脑肿瘤患者术后发生脑脊液感染的相关因素(P<0.05)。结论脑肿瘤患者术后发生脑脊液感染的相关因素较多,在临床工作中需进行具有针对性的干预措施对这些因素进行防范,降低脑肿瘤患者术后发生脑脊液感染的风险。

OBJECTIVE To analyze the related factors of cerebrospinal fluid infection in patients with brain tumor after operation.METHODS The clinical data of 225 patients with brain tumor undergoing neurosurgery at the Second Affiliated Hospital of Hainan Medical College from May 2016 to Mar.2017 were retrospectively analyzed.The related factors of cerebrospinal fluid infection of brain tumor after operation were analyzed.RESULTS A total of 79 patients in 225 patients had cerebrospinal fluid infection,and the incidence was 35.11%.There were 2 deaths in 79 patients with CSF infection,and the rest of the patients returned to normal after treatment.The age,tumor volume,external ventricular drainage,extracranial infection,malnutrition,anemia,hypoproteinemia and diabetes were related factors affecting cerebrospinal fluid infection after cerebral tumor surgery（P〈0.05）.CONCLUSION There are a variety of factors affecting postoperative cerebrospinal fluid infection in patients with brain tumors.In clinical work,targeted interventions should be taken to prevent such factors and reduce the risk of cerebrospinal fluid infection after brain tumor surgery.