冠脉介入诊疗非离子造影剂过敏样反应分析

Anaphylaxis Analysis of Nonionic Contrast Agents in Coronary Intervention

目的:分析冠脉介入诊疗非离子造影剂过敏样反应特点,并提出治疗措施。方法:随机选取我院收治1200例接受冠脉介入诊疗患者,统计发生过敏反应情况,分析出现过敏反应的临床特点,提出应对措施。结果:共18例患者出现过敏反应,发生率为1.50%。其中,轻度过敏反应发生率明显高于中度及重度(72.22%vs 16.67%、11.11%,P<0.05)。结论:冠脉介入诊疗非离子造影剂过敏样反应多以轻度为主,中度及重度相对少见,尽早发现中重度过敏反应,采取有效预防及应对措施,可降低或避免造影剂过敏反应的发生,提高诊疗安全性,临床意义重大。

Objective ： To analyze the characteristics of anaphylaxis reaction of non-ionic contrast agents in coronary intervention and to propose treatment measures. Methods ： A total of 1200 patients who received coronary intervention in our hospital were selected. The occurrence of anaphylaxis was statistieed. The clinical characteristics of the anaphylaxis were analyzed and the countermeasures were put forward. Results： A total of 18 patients had anaphylaxis, the incidence was 1.50%. Among them, the incidence of mild anaphylaxiswas significantly higher than that of moderate anaphylaxis and severe auaphylaxis （72.22% vs 16.67%, 11.11%, P〈0.05）. Conclusion： Coronary intervention diagnosis and treatment of non-ionic contrast agent allergy reaction mostly mild mainly, moderate and severe relatively rare. Effective prevention and response measures can reduce or avoid the occurrence of allergic reaction of contrast agent, improve the safety of diagnosis and treatment, and is of great clinical significance.