针刺治疗复发性阿弗他溃疡(复发性口腔溃疡/湿热蕴滞)随机平行对照研究

Acupuncture Treatment of Recurrent Aphthous Ulcers(Recurrent Oral Ulcer,Hysteresis/湿热蕴滞) Randomized Parallel Controlled Study

[目的]观察针刺治疗复发性阿弗他溃疡(复发性口腔溃疡/湿热蕴滞)疗效。[方法]使用随机平行对照方法,将80例门诊患者按就诊顺序号随机分两组。对照组40例维生素B2,10mg/次和维生素C,0.2g/次,3次/d,第一次就诊时连续用药3d,在第四周按照第一次计量继续服用3d。治疗组40例针刺(双侧天枢、足三里、合谷等),使用0.25mm×40mm毫针垂直进针,留针30min,每隔10min行针一次,1次/d;每6次休息1d。连续治疗4周为1疗程。观测临床症状、愈合速度、不良反应。治疗1疗程,判定疗效。[结果]临床疗效7d两组无显著差异(P>0.05),30d治疗组优于对照组(P<0.05)。愈合时间:<3d、>7d,两组间无明显差异(P>0.05);4~6d治疗组优于对照组(P<0.05)。[结论]针刺治疗复发性阿弗他溃疡(复发性口腔溃疡/湿热蕴滞),疗效满意,无严重不良反应,值得推广。

[Objective] To observe the effect of acupuncture on recurrent aphthous ulcers（recurrent oral ulcer/hysteresis/湿热蕴滞）. [Method] Randomized parallel control method was used. 80 outpatients were randomly divided into two groups according to the visiting order number. In the control group,40 cases of vitamin B2,10 mg/times and vitamin C,0.2 g/time,3 times/day were continuously administered for 3 days at the first visit,and continued to be taken for the first time in the fourth week for 3 days. In the treatment group,40 cases of acupuncture（bilateral Tianshu,Zusanli,Hegu,etc.） were performed using a 0.25 mm×40 mm millimeter needle in a vertical direction. The needle was retained for 30 minutes,and the needle was performed every 10 minutes once per day for 1 time every 6 days. Continuous treatment for 4 weeks is a course of treatment. Observe clinical symptoms,healing speed,and adverse reactions. Treatment 1 course of treatment,determine the efficacy. [Results] There was no significant difference in clinical efficacy between the two groups at 7 days（P〈0.05）. The 30-day treatment group was superior to the control group（P〈0.05）. Healing time：〈 3 d,〉7 d,no significant difference between the two groups（P〉0.05）; 4-6 d treatment group was better than the control group（P〈0.05）. [Conclusion] Acupuncture treatment for recurrent aphthous ulcer（recurrent oral ulcer/hysteresis） has satisfactory curative effect and no serious adverse reactions. It is worth promoting.