2型糖尿病合并糖尿病肾脏病的治疗进展

Treatment progress of Type 2 diabetes with diabetic nephropathy

糖尿病肾病是糖尿病最常见的并发症之一,是引起终末期肾脏疾病的首要病因。随着人们生活水平的改善和生活方式的改变,糖尿病患者也急剧增长,近1/3的糖尿病患者会发展为糖尿病肾病。糖尿病肾病起病隐匿,一旦出现大量蛋白尿后,进展至终末期肾脏疾病的速度会明显加快,给患者带来沉重的经济和社会负担。糖尿病肾病的治疗以控制血糖、控制血压、控制血脂、减少尿白蛋白为主,还包括饮食、运动等生活方式干预,以及纠正代谢紊乱、治疗肾功能不全的并发症、透析治疗等。本文主要从控制血糖、控制血压。

Diabetic nephropathy is one of the most common complications of diabetes and is the primary cause of end-stage renal disease. With the improvement of people＇s life and lifestyle changes, diabetes is also growing rapidly, nearly 1/3 of diabetic patients will develop to diabetic nephropathy. Diabetic nephropathy is insidious onset. Once massive proteinuria occurs, the speed of progression to end-stage renal disease will be significantly accelerated, resulting in heavy economic and social burden. The treatment of diabetic nephropathy is mainly to control blood sugar, control blood pressure, control blood lipid, reduce urine albumin, and including the lifestyle intervention of diet and exercise, as well as correction of metabolic disorders, treatment of renal insufficiency complications, dialysis treatment. This article reviews the treatment of diabetic nephropathy from three aspects： blood sugar control, blood pressure control and blood lipid control.