十二指肠Brunner腺腺瘤7例临床病理特征

Clinicopathologic characteristics of 7 cases of duodenal Brunner 's gland adenoma

分析7例十二指肠Brunner腺腺瘤(duodenal Brunner’s gland adenoma,BGA)的临床病理特征并将内镜检查的诊断结果与术后组织病理检查结果进行比较。7例患者中有症状者4例,其中伴发腹痛3例,呕吐1例,十二指肠溃疡1例,黑便1例。所有患者均接受胃镜检查,诊断BGA仅1例,息肉样病变5例,其他1例。7例患者中采用手术治疗1例,内镜下切除治疗6例。术前内镜检查结果与术后组织病理学诊断一致者仅1例。BGA是一种良性肿瘤,发生率比较低,临床表现缺乏特异性,术前诊断困难,组织病理学检查和胃镜检查对本病的诊断和治疗方法选择(外科手术或内镜下切除)具有重要价值。

The clinicopathological features of 7 cases of duodenal Brunner＇s gland adenoma（BGA） were analyzed and their corresponding post-operative histological results with pre-operation gastroscopy findings were compared. Four out of seven patients with duodenal BGA had symptoms, including abdominal pain（4 patients）, vomiting（1 patient）, duodenal ulcer（1 patient）, upper gastrointestinal hemorrhage（1 patient）. Seven patients received gastroscopy. One patient underwent surgical treatment and six patients received endoscopic resection. Only one patient had identical diagnosis in the post-operative histological results and the pre-operative gastroscopy. Duodenal BGA is a benign tumor, which has a low incidence and it＇s hard to perform accurate pre-operative diagnosis. Gastroscopy and histopathological assessment has important value in the diagnosis and determination of treatment methods（surgical operation or endoscopic resection） for the disease.