自发性腹膜炎诊治进展

Research progress of spontaneous bacterial peritonitis

自发性细菌性腹膜炎(spontaneous bacterial peritonitis,SBP)是肝硬化及重症肝炎合并腹水患者常见而严重的并发症,其临床表现不典型且诊断困难,治疗主要为经验性抗菌治疗,对于SBP存活者尚予以抗生素预防SBP复发。随着抗生素的广泛使用,近年来多重耐药性细菌引起的SBP呈增多趋势,新的细菌谱、经验性治疗及预防有待进一步研究。

Spontaneous bacterial peritonitis（SBP） is a common and serious complication of cirrhosis and severe hepatitis with ascites. The mainly therapy is empiric antimicrobial therapy. SBP survivors should use antibiotics to prevent recurrence. With the widespread use of antibiotics,SBP caused by variety of drug-resistant bacteria increased in recent years. The new bacterial spectrum,empirical treatment and prevention need further study.