糖尿病肾病研究进展

Progress of research on diabetic nephropathy

糖尿病肾病是糖尿病最严重的微血管并发症。近10年来,糖尿病肾病患者快速增长,已成为危害人类健康的公共卫生疾病。目前在欧美等发达国家,DN约占终末期肾病(ESRD)的50%,已成为尿毒症的首位原发病;在我国约占25%~40%,是患者血液透析的重要原因。因此,及时发现与防治DN,对于延缓病情进展、提高患者生活质量意义重大。

Diabetic nephropathy（ DN） is the most serious diabetic microvascular complication. In the past 10 years,the number of patients with DN has multiplied,and DN has become a severe public health disease in humans. At present,in Europe,the United States,and other developed countries,DN accounts for about 50% of end-stage renal disease（ ESRD）,and has become the first primary disease of uremia;while in China,DN accounts for about 25% to 40% of uremia,and is the main cause for hemodialysis.Therefore,the timely detection and prevention and treatment of DN is of great significance for delaying progression of the disease,and improving the quality of life of patients.