某院2014—2016年抗肿瘤药物应用分析

Analysis of Application of Antitumor Drugs in Some Hospital from 2014 to 2016

目的评价2014—2016年某院抗肿瘤药物的使用状况。方法采用药物经济学方法对该院2014—2016年间抗肿瘤药物应用情况进行回顾性分析。结果抗肿瘤药物的销售金额呈逐年增长趋势,金额居前3位的药物种类分别是抗肿瘤辅助药物、影响微管蛋白的抗肿瘤药物以及影响核酸生物合成的抗肿瘤药物;金额居前2位的药品分别是托烷司琼盐酸盐针和多西他赛针;用药频度居前3位的药品分别是甲氨蝶呤片、他莫昔芬枸橼酸盐片和托烷司琼盐酸盐针;日均用药金额居后位的药品是托烷司琼盐酸盐针和多西他赛针。结论某院抗肿瘤药物的使用情况基本合理,趋向于选择高效、低毒的抗肿瘤药物。

Objective To evaluate the use situation of antineoplastic drugs from 2014 to 2016. Methods Collecting the frequency and the consumption sum of antitumor drugs used in the hospital during 2014-2016. All the data were analyzed with pharmaco-economic methods. Results The consumption sum of antitumor drugs was in a increase trend. The top three kinds ranked by consumption sum were respectively antitumor assistant drugs,interfering tubulin antitumor drugs and interfering nucleic acid biosynthesis of antitumor drugs. The top two drugs ranked by consumption sum were respectively tropisetron hydrochloride injections and docetaxel injections. The top three drugs ranked by DDDs were respectively methotrexate tablet,tamoxifen citrate tablets and tropisetron hydrochloride injections. The bottom two drugs ranked by DDC were respectively tropisetron hydrochloride injections and docetaxel injections. Conclusion The utilization of antitumor drugs in the hospital is basically reasonable,and antitumor drugs with high efficiency an low toxicity are more likely to be applied and selected.