SPECT／CT定量技术新进展

New progress in SPECT/CT quantitative techniques

SPECT一直被认为不能进行定量分析，但SPECT／CT、物理校正（光子衰减、散射等技术）及图像重建算法等技术的出现推动了SPECT／CT定量技术的发展，目前SPECT／CT已经可以进行类似PET的定量分析。多种技术的整合使SPECT／CT在图像采集及处理方面的性能进一步提高，使定量更加准确。笔者主要对SPECT／CT的硬件、物理校正、图像重建算法的临床应用及不足进行综述。

SPECT has always been considered as a technique thas unsuitableat cannot be used for quantitative analysis. The However, the appearance of such technologies, e.g., as SPECT/CT, physical correction （such as photon attenuation and scattering）, and image reconstruction algorithms, haves promoted the development of SPECT/CT quantitative technology development. The direct integration of muhiple technologies allows the further improvement of SPECT/CT to further improve performance in image acquisition and processing, thereby ensuring more accurate quantification. The authors mainly summarized the SPECT/ CT hardware, physical correction, image reconstruction algorithm, and clinical application and insufficiency.